Fragile X Syndrome


Description: (TNR, 12, Bold)
Fragile X is a Dominate genetic disease and women (Mothers) are carriers of Fragile X. Boys (Fathers) are more likely to get infected with Fragile X more than girls get infected. The body parts that change are many things. Your face becomes longer; your ears are prominent now, a high-arched palate, hyper extendible finger joints and many others. Your thumbs become double-jointed and you have flat feet. Your low muscle tone is changed to this after Fragile X.

Inheritance:
This disease is inherited when the male has offspring with a female. The men have the disease but are predominantly affected. The women (mothers) are the obligatory carriers. Fragile X affects 1 out of 2000 males and 1 out of 259 females. Females carrying one copy of Fragile X can transmit to both son/daughters. In this case there is a X linked gene and is in a dominate condition. Males with Fragile X cannot transmit because the male has the y chromosome.



Symptoms:
The symptoms of Fragile X include elongated face, large or protruding ears, flat feet, large testes, and low muscle tone. Fragile X can include intelligence problems, social/emotional problems, and speech problems.



Daily Life:



Diagnosis:
Fragile X is passed through person through person usually through birth. The mom is the only one that can transmit the disease because the mom has the X chromosome needed. The male can’t transmit Fragile X because the male has the Y chromosome.


Treatment:
There is no definite treatment that will get rid of Fragile X, but there are various ways to minimize the symptoms. Some treatments include educational options, therapeutic methods, and medication options. There is any time you can treat this disease of Fragile X. It is never too late to benefit from the treatment.



Research:
The research of Fragile X is leading to medication to help slow down the symptoms and affects. Some other treatments include educational treatment options, therapeutic treatment options, and medication treatment options. These treatment ways help slow down the Fragile X syndrome and it is benefiting from Fragile X syndrome.




Additional Facts:
Fragile X syndrome is the most common disease and affects 1 out of 4000 males. Fragile X affects 1 out of 8000 females. Males can’t transmit Fragile X because the males have the Y chromosome. Females are the only ones who can transmit the disease because females have the X chromosome needed. Fragile X is an X–linked disease and a dominate disease. Offspring has a 50% chance of inheriting the syndrome from the parents.




Punnett Square:
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Pedigree Chart:


Alex_S_pedigree_chart.PNG




Resources:

Include hyperlink to websites that you used as part of your research
http://en.wikipedia.org/wiki/Fragile_X_syndrome
http://ghr.nlm.nih.gov/condition/fragile-x-syndrome
http://mdfragilex.org/index.html