Description
When you look at hemophilia at a glance it’s just a blood clotting disorder. Hemophiliacs are in danger of getting internal and external cuts which can cause the patient to bleed out. Some bleeding can be spontaneous. Hemophilia can begin any where from birth to thirty. The entire body is vulnerable to non stop bleeding. Internal bleeding can be spontaneous or can be caused by blunt trauma. When blunt trauma occurs bleeding can begin in a joint or even a muscle.

Inheritance:
Hemophilia can be caused by a mutation in the genes. Parents don’t have to have hemophilia to pass the disease to their children. A parent can simply be a carrier and not even know it until the child is born. This disease is extremely rare and can change a person’s life. Hemophilia is obviously (due to the fact that it’s genetic) not contagious. One in every five thousand children is born with hemophilia. Usually there is only one letter in a patient’s genetic code that can cause this disease.

Symptoms:
In the end the only symptom of hemophilia is the blood clotting factors in the patient’s blood are missing or dormant. In some patients the pain from blunt trauma can last longer; however, this is not a common symptom. This disease commonly causes patients to fall into a deep depression due to the life long effects. Without clotting factors in the blood patients are at an extremely high risk of bleeding to death from even the smallest cut.



Daily Life:



Diagnosis:
When a doctor tests for hemophilia the doctor must first rule out all other blood disorders and diseases. The doctor has a multitude of options to use for testing the patient. A family tree can help the doctor in deciding the likelihood of the patient actually having hemophilia. The doctor can take a blood sample and put the sample into some plasma then check for any anomalies. When it’s available in the near future the doctor can check the patient’s genetic code. If the doctor knows the patient has hemophilia he/she must then figure out which type of hemophilia the patient has. Hemophilia can come in three types: A, B, and C. A is the most common and lest severe type of hemophilia. B is the middle of the three types of hemophilia. C is the least common and most severe type of hemophilia. A doctor can check for hemophilia through a DNA test.


Treatment:
Hemophiliacs usually go to the hospital (as I previously mentioned) on a weekly basis for clotting therapy. With these artificial clotting factors a hemophiliac can get a cut and the clotting factors will close it up. The body does not reproduce these factors so these factors must constantly be replaced at a hospital. For their safety most hemophiliacs are home schooled in case of a bleed. The human body contains inner protection called inhibitors also know as antibodies. These antibodies can sometimes attack the artificial clotting factors. This can make it almost impossible for the treating doctor to give the patient any clotting factors. Some patients have dormant clotting factors in their bodies that can be awakened by a drug injected by the treating doctor.


Research:
Most of the research in hemophilia has been through mice. Break trough’s have happened and have been more frequent as time has progressed. Since 1965 doctors have been researching on rats for a cure for hemophilia. Since the begging of this research hemophiliacs world wide have been given drugs and clotting factors to help improve the quality of their lives. Before these breakthroughs occurred a Hemophiliac would die from a small cut. Humans have built up a vast amount of knowledge on this disorder but there is still much to learn.

Additional Facts:
Hemophilia is a blood disorder that causes the infected patient’s blood to not clot putting the infected in danger of bleeding out. Hemophilia is from the language of Greek. Hemophilia translates to haimaphilia which translates to blood to love tendency to. The translation is weird (like most translations from thousand year old languages are) but it essentially means a love to bleed. Up until the recent fifty years hemophilia was not very well know.

Punnett Square:


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Pedigree Chart:


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Resources:

Include hyperlink to websites that you used as part of your research.



Site # 1
Corporation: Dolan DNA learning center
Web site title: www.ygyh.com/
Article title: Hemophilia
URL: http://www.ygyh.org/hemo/whatisit.htm
Date of website: 2002
Date information received: 5/9/11

Site# 2
Corporation: Genetics home reference
Web site title: Genetics home reference
Article title: Hemophilia
URL: http://ghr.nlm.nih.gov/condition/hemophilia
Date of website: 1995-2011
Date information reviewed: May/8/2011

Site #3
Corporation: Kids Health
Web site: kidshealth.org
Article title: Hemophilia
URL: http://kidshealth.org/parent/medical/heart/hemophilia.html
Date of website: 1995-2011
Date information received: 5/13/11
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