Neprogenic Diabetes Insipidus
Description:
Nephrogenic Diabetes Insipidus is a disease where the Kidney cannot conserve water. It’s also a rare form of diabetes. You urinate in large amounts when having this disease, and to make up for the water lost you would drink an excessive amount of water.
Inheritance: Nephrogenic Diabetes Insipidus is an X-linked disorder. The mother can give the disorder to her sons. The daughters would be carriers. A man with the disorder cannot give the disorder to his sons but can give his daughters the gene making them carriers.
Symptoms:
The symptoms of Nephrogenic Diabetes Insipidus are extreme thirst, excessive urine, unexplainable weakness, lethargy, fatigue, and irritability. Symptoms would be high if you live in an overly hot climate. Living in a hot climate with this disorder would cause a lot of trips to the hospital during the summer from dehydration from sweating and going to the bathroom excessively.
Daily Life:

Diagnosis:
This disorder is diagnosed when the daughter/son is an infant because symptoms show early in infancy. It is also diagnosed by taking blood and urine tests.
Treatment:
There is no cure for this disorder but it is treatable. A treatment for this disorder is to have plenty of water around and constant access to the bathroom. The commonly used drugs to treat this disorder are HCTZ and indomethacin. Also living in a cooler climate would help as well.
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Additional Facts:
Nephrogenic Diabetes Insipidus

Punnett Square:

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Pedigree Chart:


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Resources:

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