Progeria
Description: (TNR, 12, Bold)
Progeria is a deadly genetic condition which causes accelerated aging. When born the Progeria host look healthy until the child is about 18 to 24 months old then they begin to show symptoms. Then once they get older it gets worst like failure to growth, loss of body fat and hair, aged-looking skin, and stiffness in joints. They also experience occasional hip dislocation, generalized atherosderosis, heart disease, and stroke.

Inheritance:
HGPS is not usually inherited or passed down by family members. HGPS is a “Sporadic autosomal dominants” mutation. This means that for a family with one child with HGPS non one sibling have the same chance of having HGPS as any other child in family. HGPS is caused by a mutation of the gene called LMNA or lamin A. LMNA is a protein that holds the nucleus of a cell together. A defective LMNA protein makes the nucleus unstable and that cellular instability appears to lead to the process of premature aging in Progeria.


Symptoms:
Some Symptoms of Progeria is unusual prominent veins of the scalp which causes head swelling. They get loss of the layer of fat beneath the skin. Also Progeria host receive joint stiffness and skeletal defects. Lastly widespread thicken and loss of elasticity of artery walls.


Daily Life:


Diagnosis:
To become an official Progeria host you must have the LMNA genetic test. They come to conclusion if u show symptoms of Progeria and you don’t pass the genetic this means your gene LMNA has corrupted and you are diagnosis with Progeria.


Treatment:
As far as treatment goes they have developed PRF a Progeria research program that came together from the many donations of people who wish to help Progeria research. In mid April 2010 they made a Progeria treatment book mainly made for parents but used by doctors to help deal with it when at home and there is no doctor around to help. They also meet with their doctor often for shots and check ups.
Research:
Though there are many researchers and doctors out there working hours at a time there is no cure for Progeria. Children with Progeria are now brought in occasionally to test on them to help research what they could to slow down the aging process. They’ve conducted a medicine to help prevent a new born from getting Progeria it’s not 100% affective but it lessens the chance of your child from it.


Additional Facts:
Progeria has reported incidence of there’s about a 1 in 4 million chance of your child getting Progeria. Progeria affects both sexes equally well as race. Progeria isn’t in just around one part of the world it’s found all over the world. They have found it in Algeria, Argentina, Australia, Austria, Belgium, Brazil, Canada, China, Columbia, Cuba, Denmark, Dominican Republic, Africa, United States, and in many more places.

Pedigree Chart:

Isaiah_s_pedigre_chart.PNG

Pictures:

progeria_child_1.jpgprogeria_child_2.jpg





Resources:
http://progeriaresearch.org/
http://en.wikipedia.org/wiki/Progeria