Huntington's+Disease-Koty.J

Huntington’s disease **Description: ** Huntington’s disease is basically nervous system disorder and it affect/controls your-brain, thoughts, movements, reflexes. It also controls you dementia. The dementia is basically a state of serious emotional and mental deterioration, of organic or functional origin. **Inheritance: ** This disease is inherited by/in an autosomal dominate pattern/trait. If the/a parent has this disease then they have a fifty percent chance of passing the disease to their child or children. This is repeated twenty-seven to thirty-five times and is not developed yet. **Symptoms: ** The symptoms (there are also stages) are behavior in movement, emotion, speech, and thoughts. Most people that have this disease will start seeing symptoms between thirty to fifty years (this disease does get worse over time). Symptoms may show earlier or later in life. **Daily Life: ** media type="custom" key="9542414" <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: 14.25pt; margin-bottom: 0pt; text-align: left; text-decoration: none; vertical-align: auto;">**<span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">Diagnosis: ** <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: 14.25pt; margin-bottom: 0pt; text-align: left; text-decoration: none; vertical-align: auto;"><span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">During pregnancy women can find out if her child has this disease. There are two tests that can be taken to see if the baby has this disease. Tests: 1-fluid sample from around the fetus, 2- taking a sample of the fetal cells from the placenta. When a child is born they can identify the disease by first doing a series of the neurological and psychological test. Genetic test confirm the diagnosis by determining if the person has HD gene mutation. These tests are not able to tell what age this person will get sick. <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: 14.25pt; margin-bottom: 0pt; text-align: left; text-decoration: none; vertical-align: auto;">**<span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">Treatment: ** <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: normal; margin-bottom: 0pt; text-align: left; text-decoration: none; vertical-align: auto;"><span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">The treatments do not slow down the progression of the disease. It can only help make the person comfortable. The medications ease the feelings of depression/anxiety and other meds control involuntary movements. Physical or speech therapy helps HD patients lead more normal lives. <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: 14.25pt; margin-bottom: 0pt; text-align: left; text-decoration: none; vertical-align: auto;">**<span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">Research: ** <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: normal; margin-bottom: 0pt; text-align: left; text-decoration: none; vertical-align: auto;"><span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">Some research shows studies including-HD genes, fetal tissues research, and work done with the P.E.T scans. Under way on several fronts these areas include- basic neurobiology: 1-clinical research 2- fetal tissue research 3- Imaging and 4- animal models. These types of tests help finding cures and how it develops/causes disease in the human body. <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: 14.25pt; margin-bottom: 0pt; text-align: left; text-decoration: none; vertical-align: auto;">**<span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">Additional Facts: ** <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: normal; margin-bottom: 0pt; text-align: left; text-decoration: none; text-indent: -0.25in; vertical-align: auto;"><span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">1- The disease was named after Dr. George Huntington; he was the first person to be diagnosed with Huntington’s in 1872. <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: normal; margin-bottom: 0pt; text-align: left; text-decoration: none; text-indent: -0.25in; vertical-align: auto;"><span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">2- In the U.S about 1 in every 30,000 people has this disease. <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: normal; margin-bottom: 0pt; text-align: left; text-decoration: none; text-indent: -0.25in; vertical-align: auto;"><span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">3- Huntington’s disease is caused by a genetic defect on chromosome 4 <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: normal; margin-bottom: 0pt; text-align: left; text-decoration: none; text-indent: -0.25in; vertical-align: auto;"><span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">4- This defect caused part of the DNA called C.A.G repeat more times than it was suppose to. <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: normal; margin-bottom: 0pt; text-align: left; text-decoration: none; text-indent: -0.25in; vertical-align: auto;"><span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">5- This section of DNA was repeated about ten to thirty-five times\ <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: normal; margin-bottom: 0pt; text-align: left; text-decoration: none; text-indent: -0.25in; vertical-align: auto;"><span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">6- A person with Huntington’s disease, their section of DNA will repeat about thirty-six to a hundred and twenty times.

<span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: 14.25pt; margin-bottom: 0pt; text-align: left; text-decoration: none; vertical-align: auto;">**<span style="background-color: transparent; color: black; font-family: 'Times New Roman','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">Punnett Square: ** <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: 14.25pt; margin-bottom: 0pt; text-align: left; text-decoration: none; vertical-align: auto;"><span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;"> <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: 14.25pt; margin-bottom: 0pt; text-align: left; text-decoration: none; vertical-align: auto;">**<span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">Pedigree Chart: ** <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: 14.25pt; margin-bottom: 0pt; text-align: left; text-decoration: none; vertical-align: auto;"><span style="background-color: transparent; color: black; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;"> <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; line-height: 14.25pt; margin-bottom: 0pt; text-align: left; text-decoration: none; vertical-align: auto;"><span style="background-color: transparent; color: black; display: block; font-family: 'Times','serif'; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">**Resources:** <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">**<span style="background-color: transparent; color: black; font-family: 'Times New Roman','serif'; font-size: 16px; line-height: 115%; text-align: left; text-decoration: none; vertical-align: auto;">Include hyperlink to websites that you used as part of your research **<span style="background-color: transparent; color: black; font-family: 'Times New Roman','serif'; font-size: 14px; line-height: 115%; text-align: left; text-decoration: none; vertical-align: auto;">. <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">__<span style="background-color: transparent; color: blue; font-family: 'Arial','sans-serif'; font-size: 13px; line-height: 115%; text-align: left; text-decoration: underline; vertical-align: auto;">Pub Med Health: Huntington’s disease __ <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">__<span style="background-color: transparent; color: blue; font-family: 'Arial','sans-serif'; font-size: 13px; line-height: 115%; text-align: left; text-decoration: underline; vertical-align: auto;">EMedTV: Huntington’s disease __ <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">__<span style="background-color: transparent; color: blue; font-family: 'Arial','sans-serif'; font-size: 13px; line-height: 115%; text-align: left; text-decoration: underline; vertical-align: auto;">Learn Genetics: Huntington’s disease __ <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">**<span style="background-color: transparent; color: #000000; font-family: 'Times','serif'; font-size: 16px; line-height: 115%; text-align: left; text-decoration: none; vertical-align: auto;">Pictures:  ** <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">
 * < <span style="background-color: transparent; color: #000000; display: block; font-family: Times New Roman; font-size: 16px; padding-bottom: 4.35pt; padding-left: 7.95pt; padding-right: 7.95pt; padding-top: 4.35pt; text-align: left; text-decoration: none; vertical-align: auto;"><span style="background-color: transparent; color: #000000; font-family: Times New Roman; font-size: 16px; text-align: left; text-decoration: none; vertical-align: auto;">Chromosome number 4 ||